Search results for "Contact allergens"

Kontaktallergie und Toleranz

2002

The contact dermatitis is a frequent occupation-related skin disease, which causes considerable distress in affected persons and immense cost for the society. In the last decades several murine systems of tolerance to contact allergens have been established to analyze the underlying immunological mechanisms and to develop new prophylactic and therapeutical strategies. The model of low zone tolerance to contact allergens may offer the advantage to investigate the physiological situation in humans. For the induction of the low zone tolerance subsensitizing doses of haptens were epicutaneously applicated onto the skin inducing antigen-specific CD8+ Tc2 suppressor cells.

Screening contact allergens from cosmetics using an optical biosensor

2006

Patch testing in children--recommendations of the German Contact Dermatitis Research Group (DKG).

2007

Summary Allergic contact dermatitis occurs frequently in children. Patch testing is needed to identify the responsible allergens and should be performed in children. We recommend a panel of 12 contact allergens as a standard series in children from 6–12 years. Four additional contact allergens should be tested in case of a positive history or suggestive clinical picture. For patch testing in children, the allergens should be applied for 24 hours and the readings should be performed at 48 and 72 hours. Standardized patch testing makes it possible to systematically investigate allergic contact dermatitis and identify relevant allergens in children.